A hyperbranched dopamine-containing PEG-based polymer for the inhibition of α-synuclein fibrillation
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چکیده
منابع مشابه
A hyperbranched dopamine-containing PEG-based polymer for the inhibition of α-synuclein fibrillation.
Aggregation of α-synuclein is believed to play an important role in Parkinson's disease and in other neurodegenerative maladies. Small molecule inhibitors of this process are among the most promising drug candidates for neurodegenerative diseases. Dendrimers have also been studied for anti-fibrillation applications but they can be difficult and expensive to synthetize. Here we show that RAFT po...
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ژورنال
عنوان ژورنال: Biochemical and Biophysical Research Communications
سال: 2016
ISSN: 0006-291X
DOI: 10.1016/j.bbrc.2015.12.060